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Collaboration Without Barriers. Discovery Without Delay.
Manifold’s Trusted Research Environment (TRE) applies AI to simplify secure collaboration and accelerate scientific discovery
Explore Manifold's core solutions
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Unify Every Part of the Research Collaboration Journey
Manifold’s TRE brings together the people, data, and tools that drive modern scientific discovery. Whether you're sharing commercial datasets, collaborating across institutions, or supporting population-scale research, Manifold removes the friction that slows progress while keeping sensitive data fully protected.
Commercial Data Delivery
License and share high-value datasets without losing control. CROs, diagnostics companies, and data aggregators provide governed, access-based environments where partners explore and analyze data securely — without copying, exporting, or exposing raw assets.
Cross-Institutional Collaboration
Work seamlessly with external researchers — without moving sensitive data. AMCs and research institutions grant collaborators secure access to patient cohorts, compute resources, and analysis tools, while your IP remains protected.
Population-Scale Biobanking
Harmonize multi-modal datasets across sites to accelerate precision medicine. Research consortia and national biobank programs unify genomic, clinical, imaging, and biomarker data with consistent governance, reproducibility, and scalable computational infrastructure.
Work Faster, Together
Manifold’s TRE removes operational bottlenecks that slow research teams down. By combining self-service access, integrated compute, and built-in governance, Manifold empowers researchers to move from question to insight in minutes — not weeks.
AI Exploratory Analysis
Start exploring as soon as you’re in the TRE. AI agents helps low-code users onboard to unfamiliar datasets, sanity-check hypotheses, and get fast feasibility answers backed by lightweight EDA. The work is fully inspectable—see the code and the logic—then bring in deeper high-code support only when it’s worth it.
Unified Tooling
One secure environment for AI, analytics, and bioinformatics. Researchers can use common high code data science environments and AI agents — all running inside the TRE. No data relocation. No infrastructure maintenance. Everything teams need to work lives in one governed platform.
Data Science
Give every researcher instant access to the tools, data, and compute they need. Launch notebooks, pipelines, dashboards, and exploratory analysis environments without IT tickets or provisioning delays. Manifold TRE turns slow, manual processes into intuitive, self-service workflows for scientific teams.
Scalable Workflows
Build repeatable analyses that scale from pilot studies to population-level research. Manifold’s TRE provides version-controlled environments, standardized pipelines, and lineage tracking so teams can reproduce results with scientific rigor — while increasing throughput across large datasets and multi-site projects.
Governed Access
Collaborate freely while maintaining strict security and regulatory control. Manifold enforces granular permissions, PHI protections, export controls, and immutable audit logs — all aligned with SOC 2, HIPAA, and GDPR. Sensitive data stays contained, even when working with external institutions.
Collaboration Ready
Keep researchers, data scientists, and collaborators in sync — no matter where they work. Shared workspaces, unified data catalogs, and built-in governance ensure that every participant sees the same data, logic, and results. This alignment eliminates duplication, reduces errors, and accelerates collaborative discovery.
Solutions
Fit-for-purpose solutions for clinical research leaders in cancer and rare disease.
Cancer Observational Study
Streamline legacy systems and manual processes with a single study and data management platform.
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Cancer Center Biobank
Reduce and turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.
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Cancer Center Registry
Unify clinical and multimodal data on a modern platform to enable automated data preparation into a research-ready patient model.
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Rare Disease Registry
Answer research questions about diagnoses, treatments, and outcomes quickly and easily.
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