Discover Your Data. Accelerate Your Research.

Manifold’s Research Commons uses AI to unify research data, streamline discovery, and dramatically speed time-to-insight across your institution.

Unify Every Stage of the Research Data Lifecycle

Manifold’s Research Commons brings together the workflows data stewards, engineers, honest brokers, and researchers rely on daily. From discovery to ingest to compliant access, Research Commons removes the manual overhead that slows scientific progress while strengthening governance at every step.

Data Discovery

Help researchers find and understand data instantly — without exposing sensitive details. Researchers and collaborators can discover what data exists, run feasibility queries, interact with an AI agent that characterizes cohort data, and understand data lineage without accessing identifiable data. Honest brokers no longer shoulder every exploratory query.

Data Ingest & Documentation

Bring new data into the system quickly, consistently, and with AI-powered enrichment. Data owners and stewards can upload datasets easily. AI agents accelerate documentation, while transformation pipelines provide error-tolerance and alerting — reducing dependency on overstretched IT teams.

Collaboration & Controlled Access

Enable research collaboration safely, securely, and on your terms. Invite internal or external partners into governed workbenches that combine the right datasets with the right analytical tools. Collaborators can even run feasibility queries in your environment — without gaining inappropriate access.

Work Faster, With Confidence

Research Commons eliminates the manual effort historically required to discover data, prepare it, assemble compliant infrastructure, and share it responsibly. By combining AI-driven search, governed access, and integrated analytical tooling—purpose-built for human subjects research rather than generic vendor frameworks—researchers move from idea to insight in a fraction of the time.

AI Cohort Creation

Empower researchers to find data without knowing every table or schema. AI agents help form queries, interpret feasibility results, and highlight relevant attributes — reducing dependency on data stewards and honest brokers.

AI Data Exploration

Onboard to unfamiliar datasets in minutes. Our AI agent answers feasibility questions like “Was this measured?” and “Can I study this here?” while running quick exploratory analyses—histograms, simple comparisons, oncoplots —so you get started faster.

AI Assisted Ingest

Reduce the burden on IT and data owners. Upload new datasets, apply transformations, and run quality checks through intuitive, self-service tools. AI-assisted documentation makes research-ready data appear faster than ever.

Collaborative Spaces

Bring people, data, and tools together in one secure workspace. Researchers, internal teams, and external collaborators can analyze shared data using preconfigured tools — without ever downloading raw data.

End-to-End Data Lineage

See how data was created, transformed, and used — at every step. Research Commons automatically captures lineage, transformations, and usage, allowing teams to trust their results and reproduce them easily.

Governed Access

Protect sensitive data while enabling productive research. Granular permissions, audit trails, differential access paths, and export controls ensure data use aligns with IRB, regulatory, and institutional requirements.

The Results Speak for Themselves

Broad Clinical Labs needed to deliver BGE and WGS sequencing data to customers on AWS, moving beyond simple file delivery. By partnering with Manifold, they now deliver data directly to AWS where customers browse QC data, variants, and files using AI. In addition, their customers can upload phenotypic data that automatically joins with genotype data—delivering far more value than traditional file delivery.

Foundation Medicine needed to accelerate drug development for biopharma partners using their comprehensive 800,000+ patient genomic dataset. FoundationInsights® 2.0, powered by Manifold, enabled this with natural language search and advanced analytics, giving partners a one-stop shop to rapidly identify patient cohorts, explore genomic alterations, and extract insights faster than ever before.

Broad Institute's Spatial Transcriptomics Platform team needed to transform how spatial omics samples are processed and delivered to researchers, moving from manual workflows to an integrated delivery system. By partnering with Manifold, they now process samples, run spatial sequencing workflows, and deliver all outputs directly into a pre-configured workbench with CellDega software, giving researchers immediate access to interactive analysis tools.

Solutions

Fit-for-purpose solutions for clinical research leaders in cancer and rare disease.

Cancer Observational Study

Streamline legacy systems and manual processes with a single study and data management platform.

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Cancer Center Biobank

Reduce and turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.

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Cancer Center Registry

Unify clinical and multimodal data on a modern platform to enable automated data preparation into a research-ready patient model.

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Rare Disease Registry

Answer research questions about diagnoses, treatments, and outcomes quickly and easily.

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