For Population Genomics Programs

Enable Research at Population Scale

Manage consent, governance, and research access for hundreds of thousands to millions of participants—all through one secure platform.

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Trusted by Population Genomics Programs

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Scale Brings Complexity

Consent at Scale

Managing consent frameworks, return of results, and participant communication across hundreds of thousands to millions of individuals requires sophisticated infrastructure.

Program Directors

National Genomics Programs

Cross-Border Collaboration

Enabling research partnerships across countries and institutions while maintaining data sovereignty, privacy regulations, and governance requirements.

Scientific Leadership

International Cohorts

Balancing Access & Sustainability

Need to enable broad research access while generating revenue through commercial partnerships to sustain long-term operations and participant engagement.

Executive Leadership

Population Genomics Platforms

Built for Population-Scale Genomics

Manage millions of participants, enable diverse research collaborations, and maintain rigorous governance—all from one platform

Consent & Governance at Scale

Manage consent frameworks, participant communication, and governance for millions of individuals

Tiered consent and access frameworks

Complete audit trail for compliance

Data sovereignty and regional controls

Leading biobanks manage 50,000+ to 2.5 million participants with complete governance frameworks

Enable Diverse Collaborations

Support academic research, pharma partnerships, and public health initiatives through unified infrastructure

Academic and commercial access models

Cross-institutional collaboration frameworks

Self-service researcher access

First-ever cross-institution data collaboration achieved: 3+ million clinical diagnoses integrated

Scalable Data Operations

Handle massive datasets and support thousands of researchers without adding operational overhead

Cloud-scale infrastructure

Automated workflows and data delivery

Support thousands of concurrent users

60,000+ global users and 80+ petabytes of data supported across deployments

Support Your Research Mission

Academic Research Access

Enable qualified researchers to access population-scale data for discovery

Pharma & Biotech Partnerships

Support drug development and biomarker discovery with population data

International Collaborations

Enable cross-border research partnerships with data sovereignty controls

Public Health Initiatives

Support government and public health research programs

Participant Engagement

Return of results and ongoing participantc ommunication at scale

Chosen by R&D Leaders

Broad Clinical Labs needed to deliver BGE and WGS sequencing data to customers on AWS, moving beyond simple file delivery. By partnering with Manifold, they now deliver data directly to AWS where customers browse QC data, variants, and files using AI. In addition, their customers can upload phenotypic data that automatically joins with genotype data—delivering far more value than traditional file delivery.

Foundation Medicine needed to accelerate drug development for biopharma partners using their comprehensive 800,000+ patient genomic dataset. FoundationInsights® 2.0, powered by Manifold, enabled this with natural language search and advanced analytics, giving partners a one-stop shop to rapidly identify patient cohorts, explore genomic alterations, and extract insights faster than ever before.

Indiana University SCCC needed to accelerate complex cohort queries across 28,000+ patient records and 81,000+ biospecimens that were taking weeks to complete. Manifold enabled them to cut query turnaround times from weeks to minutes, empowering researchers to independently generate feasibility assessments and complete multi-dimensional genomic queries while the BC^2 team handles increased request volume without adding headcount.

Champions Oncology needed a platform that could serve both their internal R&D teams and enable commercialization of their multi-omics dataset which includes PDX models with proteomics, WES, and RNA-seq data. They found a solution with Manifold that addresses both needs: a secure platform that scales from internal collaboration to external partner access, with Manifold's AI agents accelerating data evaluation and analysis across the board.

Indiana University SCCC needed to break down data silos across IUH, Regenstrief, and IU SCCC to integrate their EHR and other modalities into a unified research data commons. Manifold enabled the first-ever cross-institution collaboration through weekly EHR syncs, creating a place where researchers—even those with low technical expertise—can now ask natural language questions of over 3 million diagnoses, cut cohorts, and perform complex analyses that previously required weeks of manual data coordination.

University of Virginia Cancer Center needed to integrate their cancer registry data—including genomics, biospecimen, and clinical data—into a unified data commons, but data requests that used to take weeks or months were bottlenecking research. Manifold's AI-powered platform cut request turnaround times from months to minutes, enabling researchers to self-serve access to 60K+ patients and 10K+ biospecimens using natural language queries—unlocking far more research capacity.

Solutions

Explore Manifold's core solutions

Cancer Observational Study

Streamline legacy systems and manual processes with a single study and data management platform.

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Cancer Center Biobank

Reduce turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.

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Solutions

Fit-for-purpose solutions for clinical research leaders in cancer and rare disease.

Cancer Observational Study

Streamline legacy systems and manual processes with a single study and data management platform.

Learn more

Cancer Center Biobank

Reduce and turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.

Learn more

Cancer Center Registry

Unify clinical and multimodal data on a modern platform to enable automated data preparation into a research-ready patient model.

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Rare Disease Registry

Answer research questions about diagnoses, treatments, and outcomes quickly and easily.

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Get Started Today

Schedule an assessment to explore how Manifold can support your research mission at population scale.

Program goals and collaboration strategy

Governance framework design

Implementation roadmap

Partnership and sustainability models