AI-Powered
Cohort Explorer

Build research ready cohorts in minutes, not months

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Solutions

Explore Manifold's core solutions

Cancer Observational Study

Streamline legacy systems and manual processes with a single study and data management platform.

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Cancer Center Biobank

Reduce turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.

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The Data Platform for Life Sciences Built for the AI Era

Scientific discovery shouldn’t stall at cohort definition. Manifold’s AI-powered cohort explorer lets researchers define inclusion and exclusion criteria using natural language, delivering instant, visual results—no SQL, no delays.

Whether you’re checking feasibility or designing complex case/control groups, Manifold moves at the speed of your questions. Built for the way scientists think, it’s the fastest way to turn data into action—and the starting point of a platform built for secure, scalable, AI-native research.

Speak Science, Not SQL

Define complex cohort criteria in natural language without coding. Our AI understands biomedical terms, helping you navigate unfamiliar datasets with ease.

Instant Visual Results

See your cohort take shape in real-time with interactive visualizations that update as you refine criteria, eliminating wait times between question and insight.

Genomic-Scale Power

Filter hundreds of millions of variants within seconds, building cohorts across massive molecular datasets instantly to accelerate your research.

Learn more about specific features:

For ResearchersFor Data Stewards

Solutions

Fit-for-purpose solutions for clinical research leaders in cancer and rare disease.

Cancer Observational Study

Streamline legacy systems and manual processes with a single study and data management platform.

Learn more

Cancer Center Biobank

Reduce and turnaround time and increase productivity by connecting biospecimen data and clinical data in a single data management platform.

Learn more

Cancer Center Registry

Unify clinical and multimodal data on a modern platform to enable automated data preparation into a research-ready patient model.

Learn more

Rare Disease Registry

Answer research questions about diagnoses, treatments, and outcomes quickly and easily.

Learn more

Built for Researchers

AI-Powered Natural Language Interface

Define cohort criteria in natural language without coding or data expertise. Our AI understands biomedical terms and research concepts, making it easy to explore and filter unfamiliar datasets.

AI Transparency & Control

Review and adjust AI-generated cohort criteria using our visual interface. Maintain full control of your cohort definitions by modifying, approving, or refining the AI's suggestions at any step.

Intuitive Visual Interface

Build inclusion/exclusion criteria using an intuitive CONSORT-style interface that mirrors familiar clinical trial design workflows.

Advanced Criteria Support

Define complex nested conditions and multi-variable logic with ease. Supports full conjunctive normal form logic for maximum flexibility in cohort definitions.

Genomic Scale

Analyze and filter hundreds of millions of variants—including germline and somatic—within seconds. Build cohorts across massive molecular datasets instantly, so you can focus on discovery rather than data wrangling.

Real-Time Visualization

Watch your cohort take shape with interactive charts and tables that update dynamically as you refine your criteria.

Instant Feasibility Assessment

Receive immediate cohort size estimates and demographic breakdowns as you build, helping you optimize your study design before finalizing.

Seamless Workflow Integration

Export cohort definitions to your preferred analysis environment or save them for future use. Continue your analysis using existing pipelines and tools.

Built for Data Stewards

Universal Dataset Compatibility

Configure the cohort explorer to work with any research dataset — including clinical, genomic, imaging, biomarker data and more. No dataset is off-limits.

Self-Service Configuration Interface

Use our intuitive configuration UI to define tables, metadata, and AI training examples. Customize visualization options, column displays, and export variables without requiring technical support.

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Flexible Data Architecture

Meet your data where it is. No need to transform or migrate data to a specific format. Whether your data follows OMOP standards or uses custom schemas, our system adapts to your existing data model with minimal requirements.

Built for the AI Era of Science

"At Manifold, AI is the bridge between the language of science and the reality of data, removing barriers so ideas can move at the speed of discovery.”

Sourav Dey, PhD

CPO + Co-founder

Ready to build faster, better cohorts—and unlock what comes next?

The cohort explorer is just one part of the Manifold platform—designed to accelerate every step of your research data journey. From AI-assisted data ingestion to batch bioinformatics and AI-agents for scientific analysis, Manifold helps teams go from raw data to actionable insight without friction.

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