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We’re on a Mission
to Apply AI To Solve Hard, Impactful Problems

Manifold engineers custom AI and data infrastructure, algorithms, and applications to solve hard, impactful problems. Some of the world’s most ambitious global companies and entrepreneurs have partnered with us to deliver outcomes in record time.

“The joint discovery and development effort enabled us to realize multiple opportunities across the enterprise in the deployment of data and AI products.”
VP Data Science,
Global Biotech Company
"Manifold’s contribution has been invaluable. Our integration of machine learning algorithms will enable the dynamic adjustment of treatment, and we are able to better deploy human support at the right time and in the right way."
Chief Medical Officer,
Digital Therapeutics Company
“Manifold achieved in 3 months and a team of 4 what could have taken 12 months and a team of 10. They have a unique ability to navigate the maze of product and architecture decisions for AI products.”
SVP Technology,
Global 500 Silicon Valley Lab
“We trust Manifold and their experience not only to deliver on promised work but also to provide solid guidance on technology, product, and implementation process.”
Chief Technology Officer,
Payer Data Management Company
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Better, Faster Health Technology R&D


Health technology R&D moves too slowly and is fraught with too many failures. This is apparent in hyped AI initiatives that don’t read out results, the crisis of reproducibility of statistical results in published studies, and botched development of critical public health data infrastructure. Health technology R&D leaders are seeking to solve hard, impactful problems at the speed of big tech companies—whether they are a head of digital technology, of R&D informatics, or of computational and data sciences.

The Stakes Are High


The cost of failures can measure into the tens of millions of dollars. Even greater still is the opportunity cost in delayed patient impact and in delayed time-to-market in a fast changing landscape.

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The Status Quo Won't Work


Yet the status quo creates daunting obstacles. Executive Committees want to see returns on early investments to get comfortable with the business case. High-flier Platforms pitch solutions to short-term pains, but at the expense of building lasting differentiation. LegacyCos on someone else’s approved vendor list make big promises despite repeated high-profile failures and missing expertise.

A New Era To Build Like A Tech Company


Engineering purpose-built AI and data applications has crossed a threshold in both speed and cost to make it possible to solve more problems than ever before and to build lasting differentiation. We’re in an era of combinatorial innovation, where readily available component parts can be combined and recombined to create many new technologies and products. This is what it means to build like a tech company.

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Why Manifold


Manifold engineers custom AI and data infrastructure, algorithms, and applications to solve hard, impactful problems. We offer Google-caliber engineers, processes, and tools. We bring together the scientific expertise of the world’s top research institutions with the product design and engineering prowess of the world’s top software companies. We are organized into units with the deep domain expertise required to solve our client’s problems: Bio+Tech for biopharma, Med+Tech for devices and diagnostics, Care+Tech for payers and providers, and Tech for everything else.

Proven Return on Investment


Some of the world’s most ambitious global companies and entrepreneurs have partnered with us to deliver outcomes in record time. We can’t say too much more, but they are happy to speak to you.

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Partnership Not Vendorship


We believe in authentic partnerships, rather than traditional vendorship. A typical client journey allows for building a trusted relationship, even while keeping the urgency of the work in front of us. Mutual reference calls and engineering workshops establish trust and respect between teams. A pilot project proves results and irons out an operating model on the path to a longer-term collaboration to solve a hard, impactful problem.

Our Values


Our values are central to the company and shapes who we partner with—whether team members, clients, or investors: Purpose-driven, Growing, Optimistic, Curious, Humble, Generous, Transparent.

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